People

Carlo Vittorio Cannistraci

Research Scientists

Junior Group Leader

Biootechnology Center

Technische Universitat Dresden (BIOTEC) 

Research Interests

Carlo is a bioengineer expert in biocybernetics. He mainly works on application of information theory and machine learning in integrative systems biology.
Methodological topics: complex systems theory, information theory, optimization theory,  machine learning, pattern recognition, systems biology, signal and image processing
Data types:  omics data (genomics, proteomics, transcriptomics and post-transcriptomics, epigenomics, etc...). Biomedical data in general
Goals:  analysis, processing, reverse engineering and modeling of complex biological systems integrating biomedical information. Biomarkers and biofunctional active modules discovery. Elucidation of molecular mechanisms in normal and diseased patients for design and planning of novel drugs and therapies

Selected Publications

Carlo Vittorio Cannistraci, Timothy Ravasi, Franco Maria Montevecchi, Trey Ideker, and Massimo Alessio. Nonlinear dimension reduction and clustering by Minimum Curvilinearity unfold neuropathic pain and tissue embryological classes. Bioinformatics (Impact factor 4.926). 2010 Sept 15; 26(18):i531-9. And selected for oral presentation in 9th European Conference on Computational Biology. Ghent, Belgium September 26-29 2010

Carlo Vittorio Cannistraci, Timothy Ravasi, Shintaro Katayama, Vladimir B. Bajic, Kai Tan, et al. An atlas of combinatorial transcriptional regulation in mouse and man. Cell (Impact factor 31.152), 140-5, 744-752, 5 March 2010.

Carlo Vittorio Cannistraci, Franco Maria Montevecchi and Massimo Alessi. Median-modified Wiener filter provides efficient denoising, preserving spot edge and morphology in 2-DE image processing. Proteomics (Impact factor 5.479). 2009 Nov;9(21):4908-19
Protein fingerprints of cultured CA3-CA1 hippocampal neurons: comparative analysis of the distribution of synaptosomal and cytosolic proteins. Corti V, Sanchez-Ruiz Y, Piccoli G, Bergamaschi A, Carlo Vittorio Cannistraci, Pattini L, Cerutti S, Bachi A, Alessio M, Malgaroli A. BMC Neuroscience (Impact factor 2.74). 2008 Apr 10;9:36.

Education

Carlo graduated from the Polytechnic of Milano in 2005 with a Master Degree in Biomedical Engineering after an internship at the Department of Biological and Technological Research (DIBIT) of the San Raffaele Scientific Institute in Milano that regarded an advanced proteomic analysis of brain synapses under the supervision of Antonio Malgaroli and Massimo Alessio. In the same year he won the Italian Championship of Finswimming in 4x100 relay and entered in the elite group of the strongest freedivers in the world with more than 150 mt in dynamic freediving.
Then he received a six month research grant from ISIB-CNR (Biomedical Engineering Institute of the National Research Council), after which he joined the Proteome Biochemistry Laboratory at the San Raffaele Scientific Institute.