People

Robert Lehmann

Postdoctoral Fellows

Research Interests

​I am trained in bioinformatics and computational biology with a particular focus on understanding the mechanisms and impact of transcriptional control. In my previous work, I leveraged bioinformatic tools in order to 1) elucidate connections of chromatin structure to transcription, 2) determine the required components of the circadian clock in cyanobacteria via comparative genomics and multimodal data integration, and 3) disseminate the circadian transcriptional responses common to all cyanobacterial strains from the strain-specific transcriptional programs. Besides bioinformatics, I engaged myself with the design of photobioreactors and optical sensors for efficient cultivation and monitoring of cyanobacteria.

My current research at the Ravasi Lab focuses on the integration of bioinformatics tools in gaining insights into genetic responses to stress in marine organisms. I use genomic, transcriptomic, and epigenomic approaches to understand the genetic response of marine organisms to the environmental changes caused by the global climate change.

Selected Publications

  • Schelling N, Wiegard A, Lehmann R, Chaudhury P, Beck C, Albers SV, Axmann IM. In Press. Minimal Tool Set for a Prokaryotic Circadian Clock.
  • Lehmann R, Childs L, Thomas P, Abreu M, Fuhr L, Herzel H, Leser U & Religion A. 2015. Assembly of a Comprehensive Regulatory Network for the Mammalian Circadian Clock: A Bioinformatics Approach. PLOS One 10, 5, e0126283.
  • Lehmann R, Machné R, & Herzel H. 2014. The structural code of cyanobacterial genomes. Nucleic Acids Research 42, 14, 8873 - 8883
  • Korenčič A, Košir R, Bordyugov G, Lehmann R, Rozman D, & Herzel H. 2014. Timing of circadian genes in mammalian tissues. Scientific Reports 4, 5782.
  • Knoop H, Gründel M, Zilliges Y, Lehmann R, Hoffmann S, Lockau W & Steuer R. 2013. Flux balance analysis of cyanobacterial metabolism: The metabolic network of Synechocystis sp. PCC 6803. PLoS Computational Biology 9, 6, e1003081.

Education

  • ​2010-2016: Ph.D. Bioinformatics, Institut für theoretische Biologie, Humboldt Universität zu Berlin / Freie Universität zu Berlin, Berlin, Germany.
  • ​2005-2007: M.Sc. Bioinformatics, Freie Universität zu Berlin, Berlin, Germany.
  • ​2002-2005: B.Sc. Bioinformatics, Freie Universität zu Berlin, Berlin, Germany.